CUSTOM ITEM: HPLC Column, Bidentate C8, 4um, 3.0mm ID x 100mm Length, 100A. Cogent TYPE-C Brand. 1 EA.
Additional Info:
The 40008‑10P‑3 Cogent Bidentate C8™ HPLC Column is a custom‑manufactured, mid‑bore analytical column designed to provide alternative reversed‑phase selectivity with enhanced resolution and reduced solvent consumption compared to standard 4.6 mm ID formats. Built on Cogent TYPE‑C™ silica hydride technology, this column delivers excellent selectivity, faster equilibration, and extremely robust column lifetime under demanding analytical conditions.
The stationary phase consists of an aliphatic C8 hydrocarbon chain bonded via two direct silicon–carbon bonds (bidentate attachment) to a silica hydride surface. This non‑traditional chemistry produces a phase that is more hydrophobic than conventional C8 columns, yet less hydrophobic than Bidentate C18™, making it an ideal choice when C18 retention is excessive but stronger retention than standard C8 is still desired. Unlike traditional silica‑based C8 phases, this column can also retain select hydrophilic compounds, expanding the method‑development window.
The 3.0 mm internal diameter allows operation at lower flow rates, significantly reducing mobile‑phase consumption, while the 100 mm length increases plate count and resolving power. This configuration provides run times similar to 4.6 mm ID columns, but with notable savings in solvent use—without requiring specialized low‑flow instrumentation.
The column is also stable at very low pH (below pH 2) without degradation, a capability that further differentiates Bidentate C8™ phases from conventional C8 materials.
Why Choose the 3.0 × 100 mm Bidentate C8™ Format
This configuration is typically selected when:
C18 columns are overly retentive
Standard C8 columns lack sufficient hydrophobic interaction
Increased resolution is needed beyond 50 mm formats
Solvent‑use reduction is desired without changing instrumentation
The combination of mid‑bore geometry and TYPE‑C™ silica hydride chemistry offers an effective balance of resolution, speed, and operating cost reduction.
Key Features
Cogent TYPE‑C™ Silica Hydride Technology
Non‑traditional reversed‑phase surface chemistry
Reduced silanol activity and secondary interactions
Faster equilibration than conventional silica‑based C8 columns
Extremely robust and reproducible column performance
Bidentate C8™ Bonding
Two‑point attachment via direct Si–C bonds
Balanced hydrophobic retention
Alternative selectivity when C18 is overly retentive
Solvent‑Efficient Mid‑Bore Geometry
3.0 mm ID × 100 mm length
Higher resolution than 50 mm formats
Lower flow rates reduce mobile‑phase consumption
No specialized low‑flow equipment required
Broad Method Compatibility
Stable at very low pH (below 2)
Compatible with aqueous‑rich mobile phases
Suitable for aggressive and unconventional analytical methods
Typical Applications
Analytical HPLC requiring alternative reversed‑phase selectivity
Hydrophobic and moderately polar compounds
Situations where C18 retention is excessive
High‑resolution method development
Solvent‑reduction initiatives and cost‑efficient workflows
Made‑to‑Order & Pricing Information
This is a custom, made‑to‑order item.
Orders cannot be canceled once placed
Custom items are non‑returnable